Current research

I use advanced computational and database approaches to investigate microbial genomes and their evolution.

SymbGeneric_closeup_2548

Genomics and evolution of coral reef symbionts

De novo genome sequencing and analysis of the coral reef symbionts: the dinoflagellates of family Symbiodiniaceae, through the Reef Future Genomics (ReFuGe) 2020 Consortium’s Sea-quence Project and subsequent Discovery Projects funded by the Australian Research Council. We are interested in the evolutionary transition of dinoflagellates from free-living to establishing symbiosis with corals.

Key collaborators:

 


AlignmentFree

Scalable phylogenomics using alignment-free methods

Highly scalable phylogenomic approaches are needed to make evolutionary sense of the on-going deluge of sequence data. We are exploring the use of alignment-free methods in large-scale phylogenomic inference of microbial evolution as networks, beyond the conventional tree-like assumption of evolutionary history.

Key collaborators:

 


Endosymbiosis

Microbial ecology and evolution

We are interested in the innovation of microbial genomes due to adaptation, both in short-term e.g. development of antibiotic-resistance in bacteria, and in long term e.g. microbial adaptation to extreme environments, as well as the dynamics of genome evolution as impacted by endosymbiosis.

Key collaborators: